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HYPOTENSION


EMERGENCY MANAGEMENT

Complete COVER ABCD - A SWIFT CHECK  (1)
Confirm the blood pressure change is real (2)
Don't hesitate to treat as cardiac arrest
Inform and discuss with surgeon
Recheck vaporisers are off (3)
Improve posture: lie flat, elevate legs if possible
IV fluids: crystalloid bolus - 10 ml/kg, and repeat as necessary
Give vasopressor: metaraminol bolus 0.005-0.01 mg/kg IV (4)
If severe give adrenaline:  For an adult, 0.1 mg IV bolus very slowly.
                                                          For a child 0.001 mg/kg IV very slowly;
                                     titrate to clinical response,
     followed if necessary by an infusion of adrenaline
                                        For adults, 1 mg in 100 ml burette starting at 60ml/hr.
                                        For children, 1 mg in 1000 ml (1 mcg/ml), starting at 0.1 mcg/kg/minute
If erythema, rash or wheeze is evident go to anaphylaxis
If bradycardic go to bradycardia 
If desaturated or cyanosed go to desaturation
If pulseless go to cardiac arrest
Increase monitoring - ECG, arterial line, CVP, filling pressures.

FURTHER CARE

Review and treat probable cause(s)
See precipitating factors (3) to (9) below
Consider further fluid/drug therapy
Consider invasive haemodynamic monitoring
     Arterial pressures
     Filling pressures

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NOTES:
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It was judged that correct use of the algorithm would have led to earlier recognition of the problem and/or better management in 6% of 438 relevant incidents reported to AIMS.
(1) COVER ABCD accounted fully for 12% of hypotension incidents.
(2) Use a sphygmomanometer and auscultate the blood pressure. When using an arterial line, check the zero and calibration.
(3) Drugs were a factor in 26% of cases (inhalational and anaesthetic agents 7% each, opioids 5%,  suxamethonium 2%). Other drugs implicated included vasodilators, inotropes (pump malfunction), IV local anaesthetics, vancomycin, protamine and phenytoin. Vaporiser problems made up 32% of inhalational agent induced hypotension. 2% of all drug related hypotension was related to syringe or ampoule errors.
(4) Options include IV boluses of ephedrine 0.05mg/kg (especially with pregnancy).
(5) Based on reported incidents timely and effective management was best achieved by using specific algorithms in 85% of cases (cardiac arrest 25%, desaturation 21%,  bradycardia 31%, anaphylaxis 5%, non sinus tachycardia 3%). The remaining 15% required review of further possible specific causes. Multiple causes were involved in 23% of cases.
(6) Hypovolaemia was a factor in 2% of cases, but is often unreported. It is such a common cause of hypotension that it is not usually reported as an incident.
(7) Regional anaesthesia was a factor in 14% of cases
(8) Surgical events were a factor in at least 5% of cases. Reflex stimulation was induced by anaesthetic procedures (laryngoscopy, CVC placement) as well as surgical manipulations (mesenteric traction, eye surgery).
(9) Cardiopulmonary problems were a factor in 6% of cases.