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DRUGS/VASCULAR ACCESS


EMERGENCY CHECK

Review all ampoules/syringes/bags/burettes/diluents/ cassettes
Review all drug and cannulae labels
Systematically review all vascular access equipment, working from fluid source, via the cannula/skin interface
     to the tip of the cannula
Check that vehicles/dilutions/rates/routes are correct
Correlate doses with effects
If you have any doubts about the contents of a syringe or infusion discard and prepare a new solution.

ALWAYS CONSIDER 

Drug administration problems may be interrelated with vascular access problems (4-8)

Wrong patient 
Wrong drug (3) (6)
     Ampoule or syringe swap
     Known allergy
Right drug (3) (6)
     Wrong dose/rate
     Wrong diluent/dilution
     Wrong time
     Wrong route/site
Failure of intended delivery (4) (5)
     Malpositioned cannula tip (4)
     Bag/syringe/burette empty
     Cannula disconnected/blocked/kinked
     Line disconnected/blocked/kinked
     Back flow (up a "Y piece")
Unintended delivery (6)
     Drug flushed from dead space of IV line or cannula (7)
     Drip/pump delivering drug inadvertently (8)
     "Flushing" syringe containing drug
     Someone else giving the drug (3)
     Check for any unrecognised cannulae in situ (5)


BEWARE
Any syringe containing relaxant
Haematoma/extravasation
Inadvertent intra-arterial placement
Pneumothorax, haemothorax, hydrothorax
Nerve damage
Dysrhythmias (cannula tip in heart)
Cannula dead space


NOTES:
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The figures reported here are based on an analysis of 1199 drug and 128 access problems reported to the first 4000 AIMS anaesthesia incidents
(1) Problems with drug administration thus comprised 30% of all 4000 reports to AIMS. The incidence of errors rises markedly with polypharmacy.
(2) major morbidity in 25% of drug reports. death in 1.25%.
(3) Contributing factors:
          error of judgement 13%
          inattention 11%
          haste 10%
          communication problem 9%
          drug label problem 5%
          fatigue 3%
(4) Approach the diagnosis of vascular access problems from a "geographical perspective":
          infusion device/fluid
          fluid line/equipment
          line dead space
          catheter/skin interface
          peripheral vascular tree
          central vascular space
          staff and environment
     51% of the 128 cases involved a fault at the catheter/skin interface. In 15% of these the cannula was inserted by
     someone other than the anaesthesiologist. 18% involved central venous lines.
(5) Incorrect manufacture or assembly of arterial/central/peripheral lines - 8%
     Disconnection resulting in unrecognised blood loss - 6%
(6) Errors included:
          Connection of wrong infusion pump/fluid - 3%
          Over/under dosage fluid/drugs - 2% (especially adrenalin
          Drug precipitation in the line dead space - 2%
          Anaphylaxis to infusions - 2%
(7) Suxamethonium remaining in the dead space caused late paralysis upon subsequent line flushing in 6 case reports
(8) Unrecognised cannulae may be the source of disconnections, or be the route of an unknown delivery of drugs/fluids
 

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